Redox medicine: now and tomorrow – The main f

Presented by the International Society of Antioxidant in Nutrition & Health (ISANH), 24e International conference on oxidative stress reduction, redox homeostasis and antioxidants “Paris Redox 2022” will highlight the latest innovations in the redox field, as well as the future of redox medicine.

Keynote Speech and Introduction to Paris Redox 2022: Professor Helmut Sies

Known as the “Redox Pioneer” and having founded the concept of “Oxidative Stress”, Pr Helmut Sies, Heinrich Heine University Düsseldorf, Germany, will join Paris Redox 2022 for an introductory note: Redox medicine: now and tomorrow; the role of physiological redox signaling. He will mention some future pharmacological approaches that focus on rigorously selective modulation of enzyme oxidant sources and sinks, employing new tools in mechanistic studies and omic capabilities for targeted manipulation and delivery (e.g., nanomedicine redox).

Paris Redox 2022 speakers:

Session 1 – Redox 2022: Recent Advances & Perspectives

Miriam Margherita Cortese-KrottHeinrich Heine University Düsseldorf, Germany – The role of red blood cells in the regulation of vascular tone and blood pressure

Ivan Gout, University College London, UK – Antioxidant function of a key metabolic integrator coenzyme A in the cellular response to oxidative or metabolic stress

Marcelo Alves da Silva Mori, University of Campinas, Brazil – Regulation of oxidative metabolism and stress responses through small RNA biogenesis

Session 2 – Inter-talk Mitochondria-Microbiota & Redox

Laurent Chatre, ISTCT, CNRS, University of Caen-Normandy, France – Reactive Species Interactome-Mitochondria-Microbiota triangle: a whole new perspective on Redox Signaling & Medicine

Mariana Xavier Byndloss, Vanderbilt University Medical Center, USA – Disruption of gut microbiota and epithelial interactions as a key factor in non-communicable diseases

Session 3 – Redox, Immunity & Aging

Carole Nico, Cochin Institute – INSERM U1016, University of Paris, France – ROS and adaptive immunity

Luis Sobrevia, Pontificia Universidad Católica de Chile, Chile – Gestational diabetes mellitus and fetal endothelial dysfunction

Larissa Van Ejik, Groningen University Medical Center, Netherlands – The relationship between oxidative stress and vaccination against COVID-19

Stephane Tang, Philipps-Universität Marburg, Germany – The impact of dynamins on the integrity and function of mitochondria in ferroptosis

Session 4 – Nrf2 Signaling Pathway

Anna Grochot-Przeczek, Jagiellonian University, Poland – New atypical functions of Nrf2 and Keap1 in endothelial cells

Lie Gao, University of Nebraska Medical Center, USA – Nrf2 skeletal muscle and its role in exercise-induced cardiovascular protection: an extracellular vesicle mechanism

Gerasimos Sykiotis, University of Lausanne, Switzerland – Impact of Keap1/Nrf2 signaling on thyroid physiology and disease

Session 5 – Redox Medicine & Innovations 2022

Kenneth Olson, Indiana University, USA – Effect of “antioxidant” nutraceuticals on cellular sulfur metabolism and signaling: an alternative therapeutic approach

Nicholas Morton, University of Edinburgh, UK – Treatment of sulfide donors in diabetic animals

Pierre Nagy, National Institute of Oncology, Hungary – Reprogrammed transsulfuration promotes basal mammary tumor progression via realignment of cellular cysteine ​​transsulfuration

Charareh Pourzand, University of Bath, UK – Targeting redox-active iron in psoriatic skin, a new approach for the topical treatment of plaque psoriasis

Paul Winyard, University of Exeter School of Medicine, UK – Nitrate Metabolism in Human Health and Disease

Arno Bourgonje, Groningen University Medical Center, Netherlands – Personalized Redox Medicine in Inflammatory Bowel Diseases

Session 6 – Ocular disorders & redox medicine: recent advances & perspectives

Julie Lim, University of Auckland, New Zealand – Therapeutic insights to delay the onset of cataracts

Francisco Javier Romero, General Hospital of Requena, Spain – Oxidative stress: Involvement on the cornea and the retina

Elora Vanoni, The Vision Institute, France – Oxidative stress and energy failure: characteristics common to 3 different mouse models of abnormalities of the retinal pigment epithelium

Albert Augustine, Klinikum Karlsruhe, Germany – Oxidative processes in diabetic retinopathy

Session 7 – Fertility & Redox Medicine: Recent Advances and Therapeutic Potential

Cristian O’Flaherty, McGill University, Canada – Personalized antioxidant therapies, a new approach for male infertility

Carla Taton, University of L’Aquila, Italy – Mitochondrial sirtuins in reproduction: focus on female fertility

To access more information about the full program with all short oral and poster presentations, workshop, speakers and many more, please visit the website: https://www.isanh.net/.